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65 Best & Most Active Missouri Venture Capitalists (VC)

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Venture Capitalists (VC) play an important role in the startup ecosystem. We have curated a list of the top Missouri Venture Capitalists (VC). We have tried to select a variety of different types of investors across a variety of niches.

This list is designed to show off the investors with exceptional track records, industry experience and a unique understanding of the ecosystem.

Top Missouri Venture Capitalists (VC)

Data sourced from Crunchbase and SemRush.


Cultivation Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture, Seed

Cultivation Capital is a venture capital firm managing funds focused on software, agriculture, geospatial, and health tech startups.


SixThirty

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Convertible Note, Early Stage Venture, Seed, Venture

SixThirty is a global venture capital firm focused on investing in late seed stage FinTech, InsurTech, and Cyber Security companies.


RiverVest

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture, Late Stage Venture

RiverVest is a venture capital firm which focuses on identifying and shaping early stage life science companies to create shareholder value.


Five Elms Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Private Equity Firm, Venture Capital

Investment Stage: Late Stage Venture, Private Equity

Five Elms Capital is a global growth equity firm that invests in fast-growing B2B software businesses that users love.


Stadia Ventures

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Accelerator, Startup Competition, Venture Capital

Investment Stage: Early Stage Venture, Seed

Stadia Ventures is one of the oldest sports- and esports-focused venture firms with a sports business accelerator.


Scale

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

Scale is a Midwest-based hybrid accelerator & venture studio imparting time, knowledge, and capital in startups at the earliest stages


TRIBUS

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Corporate Venture Capital, Venture Capital

Investment Stage: Convertible Note, Debt, Early Stage Venture, Seed

TRIBUS provides technology, strategy, marketing and operations solutions for real estate brokerages around the world.


Venture360

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Private Equity

Venture360 offers powerful capital management tools that power the venture industry from application to exit.


Capital Innovators

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Accelerator, Venture Capital

Investment Stage: Early Stage Venture, Seed, Venture

Capital Innovators invests in tech-enabled startups through our nationally recognized accelerator and directly through our seed funds.


Lewis & Clark Ventures

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

Lewis & Clark Ventures is a venture capital firm that invests in Series A stage companies.


Ascend Venture Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture, Seed

Ascend Venture Capital is a venture capital company that supports data-centric companies.


Stifel Financial Corp.

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

Stifel Financial Corp. is as a financial services holding company.


Lewis & Clark AgriFood

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Private Equity Firm, Venture Capital

Investment Stage:

Lewis & Clark AgriFood focuses on the fields of agrifood, agricultural innovation, sustainability, ag-tech, and growth equity.


Countdown Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture, Seed

Countdown Capital invests pre-seed / first checks in hard tech founders.


Abstraction Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

Abstraction Capital is an early-stage venture capital firm building tools for developers and software infrastructure.


Ascension Ventures

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Corporate Venture Capital, Venture Capital

Investment Stage:

Ascension Ventures is a strategic healthcare venture fund and early-stage venture capital firm.


Prolog Ventures

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

Prolog backs companies that help all of us enjoy healthy lives in a healthy world


Firebrand Ventures

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Micro VC, Venture Capital

Investment Stage: Early Stage Venture, Seed, Venture

Firebrand Ventures combine a vast network and deep experience with startup hustle to invest in exceptional early stage software startups.


Evergy Ventures

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Corporate Venture Capital, Venture Capital

Investment Stage: Early Stage Venture, Late Stage Venture

Evergy Ventures – formerly known as GXP Investments (GXPI) – is the non-regulated investment affiliate of Evergy, Inc.


RGAx

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Incubator, Venture Capital

Investment Stage:

RGAx is the innovation accelerator of RGA, one of the worlds largest life reinsurance company.


Gefen Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

Gefen Capital is a US Israeli investment group.


4impact

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

4impact is a financial return will outperform and the global tech revolution will continue to expand rapidly.


American Century Investments

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

American Century Investments an asset management company focused on delivering investment results.


SBV Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

SBV Capital provides capital solutions for portfolio companies to assist their growth.


Oakwood Medical Investors

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture, Late Stage Venture

Oakwood Medical Investors is a venture capital fund invests in development stage medical device, biopharmaceutical and healthcare service.


Kingdom Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

Kingdom Capital’s unique platform connects its values-driven investors and investments in a comprehensive ecosystem.


OPENAIR Equity Partners

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

OPENAIR Equity Partners is a venture capital firm focused on early stage investments in mobile/wireless and connected device startups.


Cobalt Ventures

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

Cobalt Ventures is the captive private equity subsidiary of Blue Cross and Blue Shield of Kansas City.


Scout Investments

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture, Venture

Scout Investments is a company that has a broad portfolio of investors and mutual funds.


Cure8 Ventures

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

The St. Louis-based early-stage firm focused on food, wellness and health


Omicron Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Micro VC, Venture Capital

Investment Stage: Private Equity

Omicron Capital is a venture capital firm that invests in the healthcare, consumer products, and services sectors.


Arsenal Capital Management

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

Arsenal Capital Management provides investment return by identifying early capital opportunities within a fund structure.


3×5 Special Opportunity Fund

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture, Late Stage Venture

3×5 Special Opportunity Fund, L.P. specializes in later-stage companies within the healthcare and clean-tech sectors.


Holton Capital Group

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

Holton Capital Group is a family office investing in early stage technology and life science companies.


Curie Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

Curie Capital is a life science focused venture capital firm


Gilead Group

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Micro VC, Venture Capital

Investment Stage: Early Stage Venture

Gilead Group invests and provides management leadership to a portfolio of Gilead Group companies.


Oakland Capital Partners

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

Oakland Capital provide an alternative path for entrepreneurs and business owners looking for strategic assistance and capital support.


Alpine Capital Research

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

ACR is an asset management firm that provides investment management and investment advisory services through separate entities.


Mayhem Development

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

To create and invest in ideas that have the potential to disrupt markets and positively impact the lives of others.


Augury Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

Augury Capital Partners is a private equity fund that invests in late or mid-stage companies and emphasizes life sciences and financial IT.


Nidus Partners

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Seed

Nidus Partners is a venture capital firm and invests in new energy technologies.


Twin Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

At Twin Capital Partners they believe that there is never a bad time to fund a well planned, profitable business project.


Traverse Ventures

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

TRAVERSE works alongside private organizations dedicated to supporting the startup community in Cape Girardeau, MO.


Mission Peak Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

Mission Peak Capital is a real estate investment and advisory firm.


Tennant Capital Partners

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

Tennant Capital Partners is a venture capital firm focused on insurance and insurance services.


Kansas City Equity Partners

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

Kansas City Equity Partners is a private venture capital management firm.


Computime Equity Ventures

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Seed

Computime Equity Ventures provides start-up capital to dynamic B2B businesses with potential for rapid growth.


Saturday Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Private Equity Firm, Venture Capital

Investment Stage: Seed

Saturday Capital invests in high potential ideas and early stage companies in financial process technology.


Vianney Investments

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

Vianney Investments is operates as a financial services firm.


Synchrony Bio

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

Synchrony Bio is an investment fund, early-stage investing and venture development, thereby mitigating risk, amplifying value and timelines.


EG Partners

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

EG Partners is a closed-end private equity company that purchases and operates small products manufacturers.


GCRE Impact Fund

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Private Equity Firm, Venture Capital

Investment Stage: Early Stage Venture, Private Equity, Seed, Venture

Private Equity Investments


Hillcrest Bank

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

Hillcrest Bank is a company that offers banking solutions.


Tradebot Ventures

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

Tradebot Ventures Inc. is a venture capital firm specializing in startups and early stage investments.


MindShare Capital Management

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

MindShare Capital Management is a company that provides investment management services.


A.G. Edwards Capital Partners

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

The firm invests in funds that target information technology, telecommunications services, healthcare, consumer staples, manufacturing.


American Century Ventures

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

American Century Ventures specializing in investments in early stage companies.


Razorback Capital

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Micro VC, Venture Capital

Investment Stage: Early Stage Venture, Seed

Razorback Capital is a Kansas City-based venture capital firm focused on early stage investments.


Galera Angels

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Early Stage Venture

Galera Angels is an investment company focused on companies in the biotechnology sector.


Gryphon Investments

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

Gryphon Investments is a venture capital firm focusing on investments in small to mid-size growth oriented businesses.


KC Rising

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

KC Rising is looking for ways to increase the region’s economic competitiveness.


PJM Advisors

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

PJM Advisors provides investment and advisory services for growing businesses.


Venture STL

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage: Private Equity

Venture STL is the voice of entrepreneurism in Saint Louis.


Claim St. Louis

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Micro VC, Venture Capital

Investment Stage:

Claim, located in beautiful Downtown Saint Louis, is a coworking space created for entrepreneurs by entrepreneurs.


Community Development Partners

Crunchbase | Website | Facebook | Linkedin | Twitter

Investor Type: Venture Capital

Investment Stage:

Community Development Partners was organized to serve the investment needs of its membership in later 2005.

Written by Mark Kendall

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